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The Cleveland Clinic recently found a link between the widely used sugar-free sweetener xylitol and an increased incidence of cardiovascular disease such as heart attack or stroke. The study was published in the European Heart Journal. It reveals the potential risks of consuming foods and health products containing large amounts of xylitol.
Study Details and Results
Dr. Stanley Hasen, who led the study, collected data from more than 300 patients in the United States and Europe. The results showed that people with high levels of xylitol in their blood were almost twice as likely to suffer a heart attack or stroke within three years as those with lower levels of xylitol in their blood.
- An increased risk of heart disease has been linked to high levels of xylitol.
- The study involved more than 3,000 subjects from the United States and Europe.
- You can find the study in the European Heart Journal.
About Xylitol
Xylitol is a sugar alcohol that is often used as a low-calorie sweetener in sugar-free desserts (e.g., candy, gum, cakes). It is also found in some dental products (e.g., toothpaste). Because it is low in calories and does not quickly raise blood sugar levels, it is popular among those who want to reduce their intake of traditional table sugars.
However, this sweetness, which many people call innocent, has another side. Cleveland Clinic A recent study found that eating too much food increases the risk of clotting, ultimately increasing the chance of blood clots. These results have been validated by Dr. Hazen’s team through preliminary research models and patient intervention studies.
Early Research Results on Erythritol
The same research team conducted a similar study last year, identifying a link between erythritol, another sugar alcohol, and an increased risk of cardiovascular disease. Although erythritol is most common in keto-friendly and sugar-free foods in the United States, xylitol is still frequently used in many other countries.
- Xylitol is commonly found in sugar-free candies, chewing gum, toothpaste, and cakes.
- It is associated with an increased risk of coagulation and thrombosis.
- This fits with findings from last year’s study on another sugar alcohol, erythritol.
Expert Reviews
“Until we know more about its effects, think twice before consuming large amounts of xylitol,” said Dr. Chen Chenghan. MemorialCare’s Saddleback Medical CenterLikewise, Dr. Rigved Tadwalkar of Providence Saint John’s Health Center noted that while these are observational findings, there is enough concern to warrant further exploration of the matter.
“This new study adds another dimension to the ongoing debate about sugar substitutes and the impact on heart health,” commented Dr. Tadwalkar.
Study Methods and Limitations
The three-year study of more than 3,000 subjects monitored platelet activity in subjects who drank xylitol-sweetened liquids and those who drank glucose-sweetened beverages. Results showed that blood clotting ability improved significantly immediately after ingestion of xylitol.
Although this finding is eye-opening, it is important to note that observational studies only identify associations, not cause and effect. Further research is needed to fully understand the cardiovascular safety of xylitol.
- The study involved more than 3,000 people in America and Europe.
- Xylitol was found to significantly improve blood clotting compared to glucose
- This observational study only suggests an association and does not establish cause and effect.
Further research needed
Dr. Hazen emphasized that future research should focus on sugar alcohols and synthetic sweeteners. He advised consumers to be aware of the potential harms of these products and to communicate with medical experts for personalized dietary advice.
The Cleveland Clinic team recommends talking to a healthcare provider or dietitian to better understand what consuming xylitol may mean. They also emphasize the need for ongoing investigation into factors that may contribute to ongoing risk of heart disease.
Consumer Awareness and Safety Measures
Dr. Hazen assured that moderate amounts of xylitol, such as in toothpaste or a piece of gum, are unlikely to cause serious health problems. He further said people should check product labels carefully and consider using alternatives such as small amounts of table sugar, honey or fruit as sweeteners.
Recent findings from a Cleveland Clinic study suggest that consuming large amounts of this common sugar substitute carries significant health risks. While many people still choose xylitol as a popular alternative sweetener, its effects on cardiovascular risk require further exploration.
If you have any questions about your dietary choices, talk to a healthcare provider who can guide you in making healthier decisions based on your individual health concerns.
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