One study showed that 15% of people taking antidepressants experienced symptoms after stopping the medication.

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15% Drinkers Antidepressants A study published this week in The Lancet suggests that after stopping these drugs, patients will experience at least one symptom of varying severity.

A team of researchers from several German universities set out to study the symptoms that might occur when giving up these medications, comparing them to patients who might experience a negative reaction based on their own expectations (the nocebo effect).

The authors conducted a meta-analysis of 79 trials that included data from 21,002 patients, of whom 16,532 Stop taking antidepressants 4,470 people took the placebo. The average age was 45, and 72% were female.

Initially, the analysis found that 31% of people who stopped taking the compound experienced at least one Symptoms such as dizziness, headache, nausea, insomnia, or irritability3% of cases are serious.

However, when examining the results of the randomized controlled trials specifically, they found that 17% of participants who took a placebo experienced symptoms similar to those seen when they stopped antidepressant treatment.

Experts say this suggests that about half of the symptoms patients experience when stopping antidepressants may be due to the “nocebo effect” or other non-specific symptoms that can occur at any time in the general population.

Overall, the authors estimate that approximately 15% (six to seven) of patients who interrupt antidepressant treatment will experience symptoms related to discontinuation of treatment.

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The researchers, from the University of Cologne; Charité Medical School in Berlin; and the University Hospitals of Freiburg and Dresden, further determined that in 3% of cases, or one in 35, symptoms may be severe. Imipramine (About Tovlan), Paroxetine (Cerosat) and Desvenlafaxine (Pristiq) and Increased risk of severe symptoms Compared with other antidepressants, they noted in The Lancet.

The authors found no differences between trials applying a Tapering antidepressant medications However, they recalled that other previous analyses had found that tapering off medications had symptomatic benefits.

Christopher Baethge of the University of Cologne believes his findings will provide interesting data for health authorities without “causing unnecessary panic.”

Bettger added that his study does not mean that symptoms experienced by the nocebo effect are not “real,” and stressed that “all symptoms that cause patients concern or discomfort should be taken seriously, and those experiencing these symptoms should be supported.”