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A team of researchers from the University of South Carolina analyzed how hormone modulation therapy (HMT) works in breast cancer. Impact on Alzheimer’s risk or other related diseases.
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HMT is one of the most commonly used therapies for this type of cancer because it can slow tumor growth by blocking hormones and preventing them from sticking to tumor receptors. Despite the great benefits it brings, there is no consensus on the possible side effects of this treatment, Especially when it comes to cognitive impairment.
To better understand what other results might be obtained, the study was published in the medical journal JAMA Network Open. A database of people aged 65 years and above was used as a reference. After identifying women who developed breast cancer between 2007 and 2009, they categorized those who had not previously been diagnosed with Alzheimer’s disease or used HMT.
According to the survey, among nearly 18,000 patients who met the criteria, 66% of patients received hormone therapy within three years of diagnosisIn addition, the study found that 24% of patients with a history of hormone therapy use and 28% of non-hormone therapy users were diagnosed with Alzheimer’s disease during the 12-year follow-up period.
Breast cancer
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With this in mind, the experts considered the risk of death associated with: Increasing age and duration of exposure to HMT.
Among the most striking conclusions, the study showed that in a selected sample group, Hormone therapy linked to prevention of Alzheimer’s disease and related dementias (ADRD) are women aged 65 years and older with a new diagnosis of breast cancer.
The results also showed that the association between HMT and ADRD differed by age and ethnicity. In this sense, he mentioned “Both treatment approaches and individual factors should be considered when deciding on breast cancer treatment.”
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